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1

Investigation of the pharmacophore space of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) NTPase/helicase by dihydroxychromone derivatives

Chaewoon Lee, Jin Moo Lee, Na-Ra Lee, Dong-Eun Kim, Yong-Joo Jeong, Youhoon Chong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 612 KB

english, 2009

2

Structural Modification of (-)-Epigallocatechin Gallate (EGCG) Shows Significant Enhancement in Mitochondrial Biogenesis

Ha, Taewoong, Kim, Mi Kyoung, Park, Kwang-su, Jung, Woong, Choo, Hyunah, Chong, Youhoon

Journal:

Journal of Agricultural and Food Chemistry

Year:

2018

Language:

english

File:

PDF, 2.80 MB

english, 2018

3

Identification of Novel HCV RNA-dependent RNA polymerase Inhibitors Using Pharmacophore-Guided Virtual Screening

Jinyoung Kim, Ki-sun Kim, Dong-Eun Kim, Youhoon Chong

Journal:

Chemical Biology & Drug Design

Year:

2008

Language:

english

File:

PDF, 922 KB

english, 2008

4

5-HT 3 antagonists under development

Chong, Youhoon, Choo, Hyunah

Journal:

Expert Opinion on Investigational Drugs

Year:

2010

Language:

english

File:

PDF, 442 KB

english, 2010

5

Novel thienopyrimidinones as mGluR1 antagonists

Kim, Youngjae, Kim, Jeeyeon, Kim, Sora, Ki, Yooran, Seo, Seon Hee, Tae, Jinsung, Ko, Min Kyung, Jang, Hyun-Seo, Lim, Eun Jeong, Song, Chiman, Cho, YoonJeong, Koh, Hae-Young, Chong, Youhoon, Choo, Il H

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 523 KB

english, 2014

6

Water-Soluble and Cleavable Quercetin–Amino Acid Conjugates as Safe Modulators for P-Glycoprotein-Based Multidrug Resistance

Kim, Mi Kyoung, Choo, Hyunah, Chong, Youhoon

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 3.55 MB

english, 2014

7

Quercetin–POM (pivaloxymethyl) conjugates: Modulatory activity for P-glycoprotein-based multidrug resistance

Kim, Mi Kyoung, Park, Kwang-su, Choo, Hyunah, Chong, Youhoon

Journal:

Year:

2015

Language:

english

File:

PDF, 894 KB

english, 2015

8

A Smart Near-Infrared Fluorescence Probe for Selective Detection of Tau Fibrils in Alzheimer’s Disease

Seo, Yujin, Park, Kwang-su, Ha, Taewoong, Kim, Mi Kyoung, Hwang, Yu Jin, Lee, Junghee, Ryu, Hoon, Choo, Hyunah, Chong, Youhoon

Journal:

ACS Chemical Neuroscience

Year:

2016

Language:

english

File:

PDF, 1.91 MB

english, 2016

9

A Near-infrared Turn-on Fluorescent Sensor for Sensitive and Specific Detection of Albumin from Urine Samples

Kim, Yoonjeong, Shin, Eunryeol, Jung, Woong, Kim, Mi Kyoung, Chong, Youhoon

Journal:

Year:

2020

Language:

english

File:

PDF, 657 KB

english, 2020

10

Bacterial Synthesis of a Flavonoid Deoxyaminosugar Conjugate in Escherichia coli Expressing a Glycosyltransferase of Arabidopsis thaliana

Dr. Bong-Gyu Kim , Na Ri Jung , Eun Ji Joe, Prof. Hor-Gil Hur, Prof. Yoongho Lim, Prof. Youhoon Chong, Prof. Joong-Hoon Ahn

Journal:

Year:

2010

Language:

english

File:

PDF, 219 KB

english, 2010

11

ChemInform Abstract: Stereoselective Synthesis of Carbocyclic L-4′-Fluoro-2′,3′-dideoxyadenosine.

Giuseppe Gumina, Youhoon Chong, Yongseok Choi, Chung K. Chu

Journal:

Year:

2000

File:

PDF, 29 KB

2000

12

ChemInform Abstract: A Divergent Synthesis of D- and L-Carbocyclic 4′-Fluoro-2′,3′-dideoxynucleosides as Potential Antiviral Agents.

Youhoon Chong, Giuseppe Gumina, Chung K. Chu

Journal:

Year:

2001

File:

PDF, 35 KB

2001

13

L-Nucleosides: Antiviral Activity and Molecular Mechanism

Giuseppe Gumina, Youhoon Chong, Hyunah Choo, Gyu-Yong Song, Chung K. Chu

Journal:

Year:

2003

File:

PDF, 50 KB

2003

14

2′-Fluoro-4′-thio-2′,3′-unsaturated Nucleosides: anti-HIV Activity, Resistance Profile, and Molecular Modeling Studies

Youhoon Chong, Hyunah Choo, Raymond F. Schinazi, Chung K. Chu

Journal:

Year:

2004

File:

PDF, 71 KB

2004

15

ChemInform Abstract: 5-Hydroxychromone, an Alternative Scaffold for anti-HCV 1,3-Diketo Acid (DKA).

Chaewoon Lee, Kwang-su Park, Park Hye Ri Park Hye Ri, Ppark Jun Cheol Ppark Jun Cheol, Bokhui Lee, Dong-Eun Kim, Youhoon Chong

Journal:

Year:

2011

File:

PDF, 22 KB

2011

16

ChemInform Abstract: 2,6-Bis-arylmethyloxy-5-hydroxychromones with Antiviral Activity Against Both Hepatitis C Virus (HCV) and SARS-Associated Coronavirus (SCV).

Youhoon Chong, et al. et al.

Journal:

Year:

2012

File:

PDF, 32 KB

2012

17

Synthesis and biological evaluation of α- and γ-carboxamide derivatives of 10-CF3CO-DDACTHF

Youhoon Chong, Inkyu Hwang, Ali Tavassoli, Yan Zhang, Ian A. Wilson, Stephen J. Benkovic, Dale L. Boger

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 151 KB

english, 2005

18

Synthesis and biological evaluation of N-{4-[5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl}-l-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway

Heng Cheng, Inkyu Hwang, Youhoon Chong, Ali Tavassoli, Michael E. Webb, Yan Zhang, Ian A. Wilson, Stephen J. Benkovic, Dale L. Boger

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 168 KB

english, 2005

19

Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway

Heng Cheng, Youhoon Chong, Inkyu Hwang, Ali Tavassoli, Yan Zhang, Ian A. Wilson, Stephen J. Benkovic, Dale L. Boger

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 208 KB

english, 2005

20

Significant enhancement in radical-scavenging activity of curcuminoids conferred by acetoxy substituent at the central methylene carbon

Mi Kyoung Kim, Wooseong Jeong, Jihoon Kang, Youhoon Chong

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 629 KB

english, 2011

21

Effects of the aryl linker and the aromatic substituent on the anti-HCV activities of aryl diketoacid (ADK) analogues

Jinyoung Kim, Ki-Sun Kim, Hyo Seon Lee, Kwang-Su Park, Sun Young Park, Seock-Yong Kang, Soo Jae Lee, Hyung Soon Park, Dong-Eun Kim, Youhoon Chong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 598 KB

english, 2008

22

Time-dependent density functional theory-assisted absolute configuration determination of cis-dihydrodiol metabolite produced from isoflavone by biphenyl dioxygenase

Jiyoung Seo, Su-Il Kang, Mihyang Kim, Dongho Won, Haruko Takahashi, Joong-Hoon Ahn, Youhoon Chong, Eunjung Lee, Yoongho Lim, Robert A. Kanaly, Jaehong Han, Hor-Gil Hur

Journal:

Analytical Biochemistry

Year:

2010

Language:

english

File:

PDF, 617 KB

english, 2010

23

Peptide-mediated shape- and size-tunable synthesis of gold nanostructures

Jungok Kim, Youngwoo Rheem, Bongyoung Yoo, Youhoon Chong, Krassimir N. Bozhilov, Daehee Kim, Michael J. Sadowsky, Hor-Gil Hur, Nosang V. Myung

Journal:

Acta Biomaterialia

Year:

2010

Language:

english

File:

PDF, 2.51 MB

english, 2010

24

Synthesis of the 5-phosphono-pent-2-en-1-yl nucleosides: A new class of antiviral acyclic nucleoside phosphonates

Hyunah Choo, James R. Beadle, Youhoon Chong, Julissa Trahan, Karl Y. Hostetler

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 341 KB

english, 2007

25

In vitro solubility, stability and permeability of novel quercetin–amino acid conjugates

Mi Kyoung Kim, Kwang-su Park, Woon-seok Yeo, Hyunah Choo, Youhoon Chong

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 398 KB

english, 2009

26

Synthesis and anti-hepatitis C virus (HCV) activity of 3′-C-substituted-methyl pyrimidine and purine nucleosides

Won Jun Choi, Yu Min Kim, Hea Ok Kim, Hyuk Woo Lee, Dong-Eun Kim, Kwang-su Park, Youhoon Chong, Lak Shin Jeong

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 466 KB

english, 2010

27

3-O-Arylmethylgalangin, a novel isostere for anti-HCV 1,3-diketoacids (DKAs)

Hyo Seon Lee, Kwang-su Park, Bokhui Lee, Dong-Eun Kim, Youhoon Chong

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 404 KB

english, 2010

28

Effects of fluorine substitution of cytosine analogues on the binding affinity to HIV-1 reverse transcriptase

Youhoon Chong, Hyunah Choo, Chung K. Chu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 282 KB

english, 2004

29

A flavonoid gossypin binds to cyclin-dependent kinase 2

Hojung Kim, Eunjung Lee, Jihye Kim, Bora Jung, Youhoon Chong, Joong-Hoon Ahn, Yoongho Lim

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 639 KB

english, 2008

30

Aryl diketoacids (ADK) selectively inhibit duplex DNA-unwinding activity of SARS coronavirus NTPase/helicase

Chaewoon Lee, Jin Moo Lee, Na-Ra Lee, Bong-Suk Jin, Kyoung Jin Jang, Dong-Eun Kim, Yong-Joo Jeong, Youhoon Chong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 366 KB

english, 2009

31

7-O-Arylmethylgalangin as a novel scaffold for anti-HCV agents

Hyo Seon Lee, Kwang-su Park, Chaewoon Lee, Bokhui Lee, Dong-Eun Kim, Youhoon Chong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 343 KB

english, 2010

32

2-Arylmethylaminomethyl-5,6-dihydroxychromone derivatives with selective anti-HCV activity

Hye Ri Park, Kwang-Su Park, Youhoon Chong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 321 KB

english, 2011

33

Rhamnetin production based on the rational design of the poplar O-methyltransferase enzyme and its biological activities

Sunhee Lee, Soon Young Shin, Younggiu Lee, Younghee Park, Bong Gyu Kim, Joong-Hoon Ahn, Youhoon Chong, Young Han Lee, Yoongho Lim

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 647 KB

english, 2011

34

Efficient synthesis of 2-deoxy-l-erythro-pentose (2-deoxy-l-ribose) from l-arabinose

Youhoon Chong, Chung K Chu

Journal:

Carbohydrate Research

Year:

2002

Language:

english

File:

PDF, 119 KB

english, 2002

35

A divergent synthesis of d- and l-carbocyclic 4′-fluoro-2′,3′-dideoxynucleosides as potential antiviral agents

Youhoon Chong, Giuseppe Gumina, Chung K. Chu

Journal:

Tetrahedron: Asymmetry

Year:

2000

Language:

english

File:

PDF, 244 KB

english, 2000

36

Understanding the unique mechanism of l-FMAU (Clevudine) against hepatitis B virus: molecular dynamics studies

Youhoon Chong, Chung K Chu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 260 KB

english, 2002

37

The role of 2′,3′-unsaturation on the antiviral activity of anti-HIV nucleosides against 3TC-resistant mutant (M184V)

Hyunah Choo, Youhoon Chong, Chung K Chu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 290 KB

english, 2003

38

Facilitation of polymerase chain reaction with thermostable inorganic pyrophosphatase from hyperthermophilic archaeonPyrococcus horikoshii

Sun Young Park, Bokhui Lee, Kwang-Su Park, Youhoon Chong, Moon-Young Yoon, Sung-Jong Jeon, Dong-Eun Kim

Journal:

Applied Microbiology and Biotechnology

Year:

2010

Language:

english

File:

PDF, 196 KB

english, 2010

39

Location of flavone B-ring controls regioselectivity and stereoselectivity of naphthalene dioxygenase fromPseudomonassp. strain NCIB 9816-4

Jiyoung Seo, Su-Il Kang, Ji-Young Ryu, Young-Ju Lee, Ki Deok Park, Mihyang Kim, Dongho Won, Hye-Yeon Park, Joong-Hoon Ahn, Youhoon Chong, Robert A. Kanaly, Jaehong Han, Hor-Gil Hur

Journal:

Applied Microbiology and Biotechnology

Year:

2010

Language:

english

File:

PDF, 456 KB

english, 2010

40

Absolute configuration-dependent epoxide formation from isoflavan-4-ol stereoisomers by biphenyl dioxygenase ofPseudomonas pseudoalcaligenesstrain KF707

Jiyoung Seo, Su-Il Kang, Dongho Won, Mihyang Kim, Ji-Young Ryu, Suk-Woo Kang, Byung-Hun Um, Cheol-Ho Pan, Joong-Hoon Ahn, Youhoon Chong, Robert A. Kanaly, Jaehong Han, Hor-Gil Hur

Journal:

Applied Microbiology and Biotechnology

Year:

2011

Language:

english

File:

PDF, 726 KB

english, 2011

41

Cation dependentO-methyltransferases from rice

Yoon Jung Lee, Bong Gyu Kim, Youhoon Chong, Yoongho Lim, Joong-Hoon Ahn

Journal:

Year:

2008

Language:

english

File:

PDF, 422 KB

english, 2008

42

TwoO-methyltransferases fromPicea abies: characterization and molecular basis of different reactivity

Bong-Gyu Kim, Dae Hwan Kim, Su Hyun Sung, Dong-Eun Kim, Youhoon Chong, Joong-Hoon Ahn

Journal:

Year:

2010

Language:

english

File:

PDF, 681 KB

english, 2010

43

Inhibition of overexpressed CDC-25.1 phosphatase activity by flavone inCaenorhabditis elegans

Koo-Seul Kim, Ichiro Kawasaki, Youhoon Chong, Yhong-Hee Shim

Journal:

Molecules and Cells

Year:

2009

Language:

english

File:

PDF, 516 KB

english, 2009

44

Engineering of flavonoidO-methyltransferase for a novel regioselectivity

Eun Ji Joe, Bong-Gyu Kim, Byoung-Chan An, Youhoon Chong, Joong-Hoon Ahn

Journal:

Molecules and Cells

Year:

2010

Language:

english

File:

PDF, 434 KB

english, 2010

45

Novel PPARγ partial agonists with weak activity and no cytotoxicity; identified by a simple PPARγ ligand screening system

Min-Chul Cho, Dong-Hun Lee, Eun Jin Kim, Jee-young Lee, Jeong-Woo Kang, Jong Hwan Song, Youhoon Chong, Yangmi Kim, Jin-Tae Hong, Do-Young Yoon

Journal:

Molecular and Cellular Biochemistry

Year:

2011

Language:

english

File:

PDF, 459 KB

english, 2011

46

FlavonoidO-Diglucosyltransferase from Rice: Molecular Cloning and Characterization

Bong-Gyu Kim, Na Yeon Kim, Jeong Ho Kim, Kazuya Akimitsu, Youhoon Chong, Joong-Hoon Ahn

Journal:

Journal of Plant Biology

Year:

2009

Language:

english

File:

PDF, 247 KB

english, 2009

47

Characterization of PhenylpropanoidO-Methyltransferase from Rice: Molecular Basis for the Different Reactivity Toward Different Substrates

Su Hyun Sung, Bong-Gyu Kim, Youhoon Chong, Joong-Hoon Ahn

Journal:

Journal of Plant Biology

Year:

2011

Language:

english

File:

PDF, 271 KB

english, 2011

48

Plant FlavonoidO-Methyltransferases: Substrate Specificity and Application

Bong-Gyu Kim, Su Hyun Sung, Youhoon Chong, Yoongho Lim, Joong-Hoon Ahn

Journal:

Journal of Plant Biology

Year:

2010

Language:

english

File:

PDF, 220 KB

english, 2010

49

Studies of molecular mechanism of Tenofovir against 3TC- and AZT-resistance mutant HIV-1 reverse transcriptase

Youhoon Chong, Nagaraju Akula, Chung K Chu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 335 KB

english, 2003

50

Enhanced Stability and Intracellular Accumulation of Quercetin by Protection of the Chemically or Metabolically Susceptible Hydroxyl Groups with a Pivaloxymethyl (POM) Promoiety

Kim, Mi Kyoung, Park, Kwang-Su, Lee, Chaewoon, Park, Hye Ri, Choo, Hyunah, Chong, Youhoon

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.23 MB

english, 2010